Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858621 | 0.90 | MAPT (0.48) | NTRK1GRM5MAPTRAB9AXBP1 | |
| SCHEMBL2849954 | 0.87 | MAPT (0.46) | NTRK1GRM5MAPTRAB9AXBP1 | |
| SCHEMBL2856128 | 0.85 | GRM5 (0.46) | NTRK1GRM5MAPTRAB9AXBP1 | |
| SCHEMBL2858606 | 0.79 | P2RY1 (0.47) | MAPTPOLBEPHX2P2RY1 | |
| SCHEMBL2856867 | 0.77 | NPC1 (0.53) | MAPTRAB9AHTR2AP2RY1 | |
| SCHEMBL2861646 | 0.77 | NPC1 (0.42) | MAPTRAB9ANPSR1HTR2AP2RY1 | |
| SCHEMBL2853031 | 0.76 | MAPT (0.41) | MAPTNPSR1POLBP2RY1 | |
| SCHEMBL2855275 | 0.76 | MAPT (0.45) | MAPTRAB9AEPHX2P2RY1 | |
| SCHEMBL2861443 | 0.75 | MEN1 (0.47) | NTRK1MAPTNPSR1P2RY1 | |
| SCHEMBL2856517 | 0.75 | MAPT (0.42) | MAPTPOLBP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |