Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854269 | 0.91 | RAB9A (0.46) | NPC1RAB9AMAPTGAABRAF | |
| SCHEMBL2856867 | 0.89 | NPC1 (0.53) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL2854572 | 0.88 | RAB9A (0.44) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL2853595 | 0.86 | LMNA (0.44) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL2854620 | 0.86 | CA1 (0.43) | RIPK1 | |
| SCHEMBL2859362 | 0.86 | P2RX1 (0.48) | MAPTGAAKDM4EBRAFNPY5R | |
| SCHEMBL2855275 | 0.84 | MAPT (0.45) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL2852799 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9AMAPTKDM4EBRAF | |
| SCHEMBL2857337 | 0.82 | KMT2A (0.43) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL2858606 | 0.81 | P2RY1 (0.47) | MAPTGAAKDM4EP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |