Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 9/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854497 | 0.89 | NPY5R (0.44) | MAPTGAAKDM4ENPY5RMET | |
| SCHEMBL2858606 | 0.88 | P2RY1 (0.47) | MAPTGAAKDM4EP2RY1MET | |
| SCHEMBL2857444 | 0.83 | ALDH1A1 (0.42) | MAPTGAAKDM4ENPY5RALDH1A1 | |
| SCHEMBL2853031 | 0.83 | MAPT (0.41) | MAPTGAAKDM4EP2RY1MET | |
| SCHEMBL2850389 | 0.81 | NPY5R (0.40) | MAPTGAAKDM4ENPY5RALDH1A1 | |
| SCHEMBL2850763 | 0.80 | MAPT (0.48) | MAPTGAAKDM4EP2RY1MET | |
| SCHEMBL2857955 | 0.80 | NPY5R (0.42) | MAPTNPY5RALDH1A1 | |
| SCHEMBL2855775 | 0.79 | P2RY1 (0.44) | MAPTGAAKDM4EP2RY1MET | |
| SCHEMBL2855275 | 0.79 | MAPT (0.45) | MAPTGAAKDM4EP2RY1MET | |
| SCHEMBL2861646 | 0.77 | NPC1 (0.42) | MAPTGAAKDM4ENPY5RP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |