Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 16/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EZH1 | Q92800 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021488 | 0.87 | EZH2 (0.50) | EZH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28609837 | 0.83 | EZH2 (0.48) | EZH2EZH1 | |
| SCHEMBL28595709 | 0.81 | LSS (0.46) | EZH2EZH1 | |
| SCHEMBL16935193 | 0.80 | ALDH1A1 (0.47) | EZH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28605092 | 0.79 | POLB (0.49) | ALDH1A1GAA | |
| SCHEMBL28607251 | 0.79 | EZH2 (0.43) | EZH2EZH1 | |
| SCHEMBL28597523 | 0.77 | EZH2 (0.41) | EZH2EZH1 | |
| SCHEMBL28597396 | 0.77 | CCR5 (0.48) | EZH2EZH1LMNA | |
| SCHEMBL29473814 | 0.76 | EZH2 (0.42) | EZH2EZH1 | |
| SCHEMBL28918826 | 0.76 | EZH2 (0.42) | EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045494-B | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2022-04-26 | — | — | CN | disclosed |
| CN-113045494-A | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2021-06-29 | — | — | CN | disclosed |