SCHEMBL2860741

SCHEMBL2860741

CC(C)(C)C1=CC(C)(C)c2cc3c(cc21)-c1cc2c(cc1C3)C(C)(C)C=C2C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2870966 0.89 PGR (0.47) PGRMAPT
SCHEMBL2870970 0.82 PGR (0.44) PGRMAPT
SCHEMBL2863971 0.75
SCHEMBL2860612 0.75 PGR (0.44) PGR
SCHEMBL2867741 0.66 PGR (0.31) PGR
SCHEMBL2870358 0.65 MAPT (0.32) MAPT
SCHEMBL19290149 0.60 RARA (0.33) PGRMAPT
SCHEMBL2863975 0.60
SCHEMBL2869771 0.59 MAPT (0.33) MAPT
SCHEMBL2867804 0.59 PGR (0.34) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834204-B2 Fluorene derivative, transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2010-11-16 US disclosed
US-20090253876-A1 Fluorene Derivative, Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer MITSUI CHEMICALS, INC. 2009-10-08 US disclosed
EP-1900715-A1 FLUORENE DERIVATIVE, TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253876-A1 Fluorene Derivative, Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer AFF4, OR10J3, DRD1 PGR 2102/4885MAPT 3445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.