⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870358 | 0.69 | MAPT (0.32) | — | |
| SCHEMBL2863971 | 0.64 | — | — | |
| SCHEMBL2873023 | 0.62 | PGR (0.44) | — | |
| SCHEMBL2870859 | 0.60 | — | — | |
| SCHEMBL2860741 | 0.60 | PGR (0.32) | — | |
| SCHEMBL2870910 | 0.58 | PGR (0.30) | — | |
| SCHEMBL2869771 | 0.56 | MAPT (0.33) | — | |
| SCHEMBL24656311 | 0.56 | — | — | |
| SCHEMBL18315273 | 0.55 | ALDH1A1 (0.44) | — | |
| Lithium SCHEMBL18315275 | 0.55 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834204-B2 | Fluorene derivative, transition metal compound, catalyst for olefin polymerization, and process for producing olefin polymer | MITSUI CHEMICALS, INC. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20090253876-A1 | Fluorene Derivative, Transition Metal Compound, Catalyst for Olefin Polymerization, and Process for Producing Olefin Polymer | MITSUI CHEMICALS, INC. | 2009-10-08 | — | — | US | disclosed |
| EP-1900715-A1 | FLUORENE DERIVATIVE, TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |