SCHEMBL28607753

SCHEMBL28607753

C=CC(=O)O[SiH](OC)OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28481070 0.84 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Methyl Ester SCHEMBL108153 0.80 HCAR2 (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28675265 0.78 ALDH1A1 (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28618494 0.75 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL2106903 0.74 LMNA (0.56) TSHRHPGDALDH1A1HSD17B10HCAR2
SCHEMBL1062929 0.74
Acrylamide SCHEMBL2578205 0.72 ALDH1A1 (0.58) TSHRHPGDALDH1A1LMNA
SCHEMBL8631308 0.72
SCHEMBL4394880 0.72 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18528934 0.72 TSHR (0.62) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114245812-B Latex for bonding fibrous structures 昕特玛德国有限公司 2024-08-23 CN disclosed
CN-113825776-A Polymers having an upper critical solution temperature in aqueous solution 波音公司 2021-12-21 CN disclosed
CN-113226379-A Nanoparticle encapsulation targeting G protein-coupled receptors in endosomes 武田药品工业株式会社 2021-08-06 CN disclosed
CN-109563343-A Resin combination uses its sheet material, laminated body, power semiconductor, plasma processing apparatus and method for making semiconductor 东丽株式会社 2019-04-02 CN disclosed