Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854992 | 0.86 | L3MBTL1 (0.43) | KMT2AMEN1ALOX15TSHRMAPT | |
| SCHEMBL2850524 | 0.84 | MAPT (0.43) | KMT2AMEN1NPSR1MAPTRAB9A | |
| SCHEMBL2852244 | 0.84 | MAPT (0.48) | KMT2AKDM4EPOLBMEN1NPSR1 | |
| SCHEMBL2858436 | 0.84 | MEN1 (0.46) | KMT2AKDM4EMEN1FFAR2MAPT | |
| SCHEMBL2854489 | 0.84 | PTGS1 (0.43) | POLBMAPTRAB9AGPR6NPC1 | |
| SCHEMBL2852163 | 0.83 | KMT2A (0.53) | KMT2AKDM4EPOLBFFAR2ALOX15 | |
| SCHEMBL2854626 | 0.82 | MAPT (0.40) | KDM4EPOLBNPSR1MAPTRAB9A | |
| SCHEMBL2850712 | 0.82 | MAPT (0.41) | KMT2AKDM4EPOLBMEN1NPSR1 | |
| SCHEMBL2860252 | 0.82 | MAPT (0.39) | KMT2APOLBMEN1FFAR2TSHR | |
| SCHEMBL2848317 | 0.81 | MAPT (0.46) | KMT2AKDM4EPOLBMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |