Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854489 | 0.93 | PTGS1 (0.43) | RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2853088 | 0.92 | NR3C1 (0.41) | L3MBTL1PTK2RAB9ANPC1TSHR | |
| SCHEMBL2853241 | 0.87 | SMN1; SMN2 (0.41) | L3MBTL1BRD4SMN1; SMN2PTK2RAB9A | |
| SCHEMBL2852244 | 0.86 | MAPT (0.48) | SMN1; SMN2MAPTGPR6CYP1A2CYP2D6 | |
| SCHEMBL2860795 | 0.86 | KMT2A (0.46) | SMN1; SMN2RAB9ANPC1TSHRMAPT | |
| SCHEMBL2854626 | 0.85 | MAPT (0.40) | SMN1; SMN2RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2850712 | 0.85 | MAPT (0.41) | SMN1; SMN2RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2855796 | 0.85 | ALDH1A1 (0.43) | L3MBTL1SMN1; SMN2PTK2RAB9ANPC1 | |
| SCHEMBL2852401 | 0.85 | L3MBTL1 (0.39) | L3MBTL1BRD4SMN1; SMN2PTK2RAB9A | |
| SCHEMBL2860252 | 0.84 | MAPT (0.39) | SMN1; SMN2TSHRMAPTGPR6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |