Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854992 | 0.93 | L3MBTL1 (0.43) | RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2853065 | 0.86 | NR3C1 (0.46) | RAB9ANPC1MAPTGAACNR1 | |
| SCHEMBL2853088 | 0.85 | NR3C1 (0.41) | SCN9ARAB9ANPC1F10MAPT | |
| SCHEMBL2852924 | 0.84 | SMN1; SMN2 (0.46) | MAPTGAAPOLB | |
| SCHEMBL2852244 | 0.84 | MAPT (0.48) | MAPTGAAPOLBNR3C1GPR6 | |
| SCHEMBL2860795 | 0.84 | KMT2A (0.46) | RAB9ANPC1MAPTPOLBGPR6 | |
| SCHEMBL2856901 | 0.83 | MAPT (0.40) | RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2860522 | 0.83 | MAPT (0.48) | RAB9ANPC1MAPTTRPV1 | |
| SCHEMBL2857550 | 0.83 | TMPRSS4 (0.45) | RAB9ANPC1MAPTGPR6 | |
| SCHEMBL2854626 | 0.82 | MAPT (0.40) | RAB9ANPC1MAPTPOLBGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |