Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7621903 | 1.00 | HDAC4 (0.39) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| Propionic Acid SCHEMBL10608795 | 0.85 | FFAR3 (0.42) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL157595 | 0.84 | — | — | |
| SCHEMBL27609354 | 0.84 | HDAC4 (0.37) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL1645488 | 0.84 | — | — | |
| Bicarbonate SCHEMBL9700991 | 0.83 | HDAC4 (0.43) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| Malonic Acid SCHEMBL28164168 | 0.82 | HDAC4 (0.41) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL261715 | 0.76 | — | — | |
| SCHEMBL1381818 | 0.76 | — | — | |
| SCHEMBL5025519 | 0.75 | ALDH1A1 (0.33) | HDAC4HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106855-B1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | NISSAN CHEMICAL IND LTD (JP) | 2012-07-11 | — | — | EP | disclosed |
| US-7700789-B2 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| EP-1632291-B1 | HETEROGENEOUS CATALYST AND PROCESS FOR PRODUCING OXIRANE COMPOUND WITH THE CATALYST | NISSAN CHEMICAL IND LTD (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-2106855-A1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | Nissan Chemical Industries, Ltd. (JP) | 2009-10-07 | — | — | EP | disclosed |
| US-20090082583-A1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| US-20070093667-A1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1632291-A1 | HETEROGENEOUS CATALYST AND PROCESS FOR PRODUCING OXIRANE COMPOUND WITH THE CATALYST | Nissan Chemical Industries, Ltd. (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-4855488-A | Process for the preparation of dicyclopentenol esters | HUELS AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093667-A1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | OXGR1, OXER1, OGFOD1 | HDAC4 1656/4885HDAC2 215/4885HDAC8 1318/4885 |
| US-20090082583-A1 | Heterogeneous catalyst and process for producing oxirane compound with the catalyst | OXGR1, OGFOD1, OGDH | HDAC4 1259/4885HDAC2 167/4885HDAC8 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.