Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL8524158 | 0.97 | ALDH1A1 (0.40) | ALDH1A1TSHRMEN1GLAMAPT | |
| Propanol SCHEMBL20590519 | 0.85 | ALDH1A1 (0.33) | ALDH1A1TSHRMEN1GLAMAPT | |
| Butane SCHEMBL29290122 | 0.80 | TDP1 (0.32) | — | |
| Propane SCHEMBL28903031 | 0.80 | TDP1 (0.32) | — | |
| Ethyl Chloride SCHEMBL4465242 | 0.78 | CTRC (0.32) | — | |
| Isopropyl Alcohol SCHEMBL20590526 | 0.71 | ALDH1A1 (0.40) | ALDH1A1 | |
| Alcohol SCHEMBL22616193 | 0.66 | ALDH1A1 (0.86) | ALDH1A1TSHRMEN1KMT2A | |
| Alcohol SCHEMBL8470225 | 0.66 | — | — | |
| Alcohol SCHEMBL5248243 | 0.66 | — | — | |
| Alcohol SCHEMBL10481768 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110174488-B | Method for detecting allergen in cosmetics | 青岛农业大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113101378-B | Cosmetic allergen detection method and allergen patch kit | 黑龙江省医院 | 2021-11-16 | — | — | CN | disclosed |