Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 10/20 | 0.76 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28614988 | 0.95 | MAPK10 (0.70) | MAPK10MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL13781543 | 0.88 | MAPK8 (0.60) | MAPK10MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL28605289 | 0.86 | MAPK8 (1.00) | MAPK10MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL13781554 | 0.84 | HCAR2 (0.68) | MAPK10MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL3712355 | 0.79 | MAPK8 (0.81) | MAPK10MAPK8KMT2AMAPK9HTT | |
| SCHEMBL28605599 | 0.79 | HCAR2 (0.70) | MAPK10MAPK8KMT2AMEN1NR1H4 | |
| SCHEMBL3712296 | 0.77 | MAPK10 (0.76) | MAPK10MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL9367263 | 0.76 | NR1H4 (0.83) | MAPK10MAPK8KMT2AMEN1NR1H4 | |
| SCHEMBL2038480 | 0.74 | L3MBTL1 (0.76) | MAPK10MAPK8KMT2AMEN1NR1H4 | |
| SCHEMBL16737208 | 0.74 | MAPT (0.49) | MAPK10MAPK8KMT2AMEN1MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |