SCHEMBL2038480

SCHEMBL2038480

O=C(Cc1ccc2ccccc2c1)Nc1cc(NC(=O)Cc2ccc3ccccc3c2)cc(NC(=O)Cc2ccc3ccccc3c2)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.76
NR1H4 Q96RI1 1/20 0.75
NLRP3 Q96P20 1/20 0.73
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
MAPT P10636 2/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
HPGD P15428 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
RIOK2 Q9BVS4 5/20 0.58
GSK3A P49840 3/20 0.58
MAPK10 P53779 3/20 0.58
MAPK8 P45983 1/20 0.58
HIPK1 Q86Z02 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9367263 0.92 NR1H4 (0.83) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL13533414 0.87 NR1H4 (0.76) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL13451638 0.86 NR1H4 (0.74) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL28869815 0.86 NR1H4 (0.79) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL13451637 0.86 NR1H4 (0.74) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL24195991 0.84 MEN1 (0.62) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL28869800 0.84 NLRP3 (0.73) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL14344626 0.84 MEN1 (0.76) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL28869801 0.82 NR1H4 (0.69) L3MBTL1NR1H4NLRP3MEN1KMT2A
SCHEMBL29936636 0.82 NR1H4 (0.69) L3MBTL1NR1H4NLRP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 EP disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 WO disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed