Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KAT7 | O95251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610616 | 0.89 | FGFR1 (0.38) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL28609740 | 0.87 | FGFR1 (0.33) | FGFR1FGFR3FGFR2FGFR4 | |
| SCHEMBL28607836 | 0.87 | FGFR1 (0.32) | FGFR1FGFR3FGFR2FGFR4 | |
| SCHEMBL28610691 | 0.86 | FGFR1 (0.31) | FGFR1FGFR3FGFR2FGFR4 | |
| SCHEMBL16659621 | 0.85 | FGFR4 (0.37) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL30745811 | 0.85 | FGFR4 (0.37) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL18138353 | 0.81 | FGFR4 (0.34) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL19633217 | 0.79 | FGFR4 (0.34) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL18138247 | 0.79 | FGFR4 (0.35) | FGFR1FGFR3FGFR2FGFR4CYP3A4 | |
| SCHEMBL18138307 | 0.78 | FGFR4 (0.43) | FGFR1FGFR3FGFR2FGFR4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400092-B | Pyrimidine derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-08-24 | — | — | CN | disclosed |