Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604098 | 0.83 | PARP10 (0.60) | MEN1KMT2ASPHK2SPHK1PARP15 | |
| SCHEMBL4638501 | 0.83 | MAOB (0.57) | MAOBCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL28607104 | 0.83 | MAOB (0.59) | MEN1KMT2AMAOBSPHK2PARP15 | |
| SCHEMBL28919880 | 0.83 | PARP10 (0.59) | MEN1KMT2AKDM4ESPHK2SPHK1 | |
| SCHEMBL6088674 | 0.81 | SLC26A4 (0.63) | MEN1KMT2AMAOBCCNB2CDK1 | |
| SCHEMBL28608319 | 0.80 | MAOB (0.62) | MEN1KMT2AMAOBSPHK2SPHK1 | |
| SCHEMBL5249598 | 0.79 | KMT2A (0.65) | MEN1KMT2AMAOBKDM4ESPHK2 | |
| SCHEMBL6088329 | 0.79 | MAOB (0.52) | MAOBCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16886114 | 0.79 | CCNB2 (0.57) | KMT2AMAOBCCNB2CDK1CDK4 | |
| SCHEMBL2087954 | 0.78 | MAOB (0.71) | MAOBCCNB2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264874-A | Substituted diaryl urea derivative and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |