Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450809 | 0.92 | NR4A2 (0.58) | SLC26A4MAOBPTGER4NR4A2MEN1 | |
| SCHEMBL6088483 | 0.89 | SLC26A4 (0.52) | SLC26A4MAOBCCNB2CDK1CDK4 | |
| SCHEMBL6091862 | 0.89 | SLC26A4 (0.52) | SLC26A4MAOBCCNB2CDK1CDK4 | |
| SCHEMBL6089332 | 0.89 | NR4A2 (0.67) | SLC26A4MAOBPTGER4NR4A2NPC1 | |
| SCHEMBL6090532 | 0.89 | SLC26A4 (0.51) | SLC26A4MAOBCCNB2CDK1CDK4 | |
| SCHEMBL4451992 | 0.88 | SLC26A4 (0.53) | SLC26A4MAOBCCNB2CDK1CDK4 | |
| SCHEMBL6090535 | 0.88 | NPC1 (0.55) | SLC26A4PTGER4NR4A2NPC1RAB9A | |
| SCHEMBL6087956 | 0.87 | PTGER4 (0.55) | SLC26A4MAOBPTGER4NR4A2FFAR1 | |
| SCHEMBL6088329 | 0.86 | MAOB (0.52) | SLC26A4MAOBCCNB2CDK1CDK4 | |
| SCHEMBL6089761 | 0.86 | GPR132 (0.49) | SLC26A4MAOBPTGER4NR4A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| CN-1183113-C | Tri-aryl acid derivatives as PPAR receptor ligands | ���ĵ�˹ҩ��¹�����˾ | 2005-01-05 | — | — | CN | disclosed |
| CN-1356983-A | Tri-aryl acid derivatives as PPAR receptor ligands | AVENTIS PHARM PROD INC (DE) | 2002-07-03 | — | — | CN | disclosed |