Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.50 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784756 | 0.83 | ASIC3 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL5653453 | 0.83 | NPC1 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL16703278 | 0.78 | MAP4K4 (0.47) | NPC1RAB9AKDM4ESMN1; SMN2SMARCA2 | |
| SCHEMBL5558891 | 0.78 | ASIC3 (0.48) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL457288 | 0.78 | LDHA (0.53) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL14909246 | 0.78 | GSK3A (0.51) | NPC1RAB9AASIC3SMARCA2SMARCA4 | |
| SCHEMBL117744 | 0.76 | LDHA (0.64) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL29604379 | 0.76 | LDHA (0.64) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL21568765 | 0.74 | LDHA (0.57) | NPC1RAB9AKDM4ESMN1; SMN2ASIC3 | |
| SCHEMBL14988841 | 0.74 | LDHA (0.62) | NPC1RAB9AKDM4ESMN1; SMN2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920177-A | Aromatic monoamine compound, cover material, and light-emitting element | 东丽先端材料研究开发（中国）有限公司 | 2021-06-08 | — | — | CN | disclosed |