Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205987 | 0.73 | ALDH1A1 (0.69) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL20069530 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL20147405 | 0.71 | MEN1 (0.71) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL28620623 | 0.70 | PTPN11 (0.50) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL15548628 | 0.64 | GAA (1.00) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL17760993 | 0.63 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL19832548 | 0.60 | SIGMAR1 (0.61) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL3023133 | 0.59 | MAPT (0.58) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL29002710 | 0.58 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL3028058 | 0.58 | MAPT (0.60) | ALDH1A1KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475531-B | Heterocyclic inhibitors of PTPN11 | 得克萨斯州立大学董事会 | 2021-08-17 | — | — | CN | disclosed |