Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437790 | 0.84 | MAPT (0.47) | GAAHTTPTPRCMAPTTDP1 | |
| SCHEMBL6902818 | 0.83 | MAPT (0.45) | GAAHTTMAPTLMNATHRB | |
| SCHEMBL29926763 | 0.83 | MAPT (0.45) | GAAHTTMAPTLMNATHRB | |
| SCHEMBL9135679 | 0.83 | ALDH1A1 (0.47) | PTPRCLMNATHRBTDP1KDM4E | |
| SCHEMBL9134842 | 0.83 | HTT (0.46) | HTTPTPRCLMNATHRBTDP1 | |
| SCHEMBL5549639 | 0.83 | PTPRC (0.42) | PTPRCTHRBTDP1ALDH1A1MAPK1 | |
| SCHEMBL9134208 | 0.83 | L3MBTL1 (0.43) | HTTPTPRCMAPTLMNAKMT2A | |
| SCHEMBL948953 | 0.83 | ALDH1A1 (0.51) | GAAHTTPTPRCMAPTLMNA | |
| Hydrochloric Acid SCHEMBL6990475 | 0.81 | MAPT (0.44) | GAAHTTMAPTLMNATHRB | |
| SCHEMBL9134040 | 0.81 | GAA (0.49) | GAAMAPTLMNATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700372-A | Preparation method of 2-substituted benzoxazole compound | 西安向阳航天材料股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-112480020-B | 2-substituted benzoxazole compound | 东华理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-113818033-B | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113818033-A | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112480020-A | 2-substituted benzoxazole compound | 东华理工大学 | 2021-03-12 | — | — | CN | disclosed |