Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926763 | 1.00 | MAPT (0.45) | MAPTGAAKMT2AMEN1PKM | |
| Hydrochloric Acid SCHEMBL6990475 | 0.98 | MAPT (0.44) | MAPTGAAKMT2AMEN1PKM | |
| SCHEMBL6909147 | 0.84 | ALDH1A1 (0.49) | MAPTGAAKMT2AMEN1KDM4E | |
| SCHEMBL29926725 | 0.84 | ALDH1A1 (0.49) | MAPTGAAKMT2AMEN1KDM4E | |
| SCHEMBL28596978 | 0.83 | TSHR (0.47) | MAPTGAAKMT2AMEN1PKM | |
| SCHEMBL28610965 | 0.83 | GAA (0.45) | MAPTGAAKMT2AMEN1PKM | |
| SCHEMBL28603994 | 0.82 | THRB (0.49) | MAPTGAAKMT2AMEN1PKM | |
| SCHEMBL9779960 | 0.81 | MAPT (0.53) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL28012387 | 0.81 | KMT2A (0.47) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL28670953 | 0.81 | HPGD (0.46) | MAPTGAAKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | claimed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |
| CN-117700372-A | Preparation method of 2-substituted benzoxazole compound | 西安向阳航天材料股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-112480020-B | 2-substituted benzoxazole compound | 东华理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-113818033-B | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113818033-A | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112480020-A | 2-substituted benzoxazole compound | 东华理工大学 | 2021-03-12 | — | — | CN | disclosed |
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | disclosed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | disclosed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | disclosed |
| EP-1023454-A1 | PROCESS FOR THE PREPARATION OF A (BETA)-LACTAM ANTIBIOTIC | DSM N.V. (NL) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020786-A1 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC | DSM N.V. (NL) | 1999-04-29 | — | — | WO | disclosed |
| EP-0228230-B1 | PROCESS FOR THE PREPARATION OF FOAMS CONTAINING ISOCYANURATE AND URETHANE LINKAGES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-13 | — | — | EP | disclosed |
| US-4771025-A | ALKALI METAL OR TETRAALKYL AMMONIUM CARBOXYLATE, ALKALINE EARTH METAL CARBOXYLATE AND OPTIONALLY AN AMINE CO-CATALYST | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-13 | — | — | US | disclosed |
| EP-0228230-A2 | Process for the preparation of foams containing isocyanurate and urethane linkages | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | GRHPR, ARL1, SUCLG1 | MAPT 4452/4885GAA 1037/4885KMT2A 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.