Benzidine

Benzidine

SCHEMBL28611517

CO.Nc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.79
ALDH1A1 P00352 5/20 0.79
TDP1 Q9NUW8 4/20 0.79
TP53 P04637 3/20 0.79
HSD17B10 Q99714 3/20 0.61
TAAR1 Q96RJ0 2/20 0.61
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
ALOX15 P16050 3/20 0.50
CA14 Q9ULX7 2/20 0.50
ACHE P22303 1/20 0.50
CA3 P07451 1/20 0.50
THRB P10828 1/20 0.50
CA6 P23280 1/20 0.50
CASP1 P29466 1/20 0.50
HIF1A Q16665 1/20 0.50
KIF11 P52732 1/20 0.50
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL28721483 0.97 CYP3A4 (0.73) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL27459735 0.89 ALDH1A1 (0.85) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL29120747 0.89 ALDH1A1 (0.85) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL2466323 0.89 ALDH1A1 (0.85) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL501952 0.89 ALDH1A1 (0.85) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL9980982 0.89 ALDH1A1 (0.85) CYP3A4ALDH1A1TDP1TP53HSD17B10
Benzidine SCHEMBL29021 0.89 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
Methyl Alcohol SCHEMBL9437744 0.89 MAPT (0.73) CYP3A4ALDH1A1TDP1TP53HSD17B10
SCHEMBL258287 0.89 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10
SCHEMBL28842081 0.89 CYP3A4 (1.00) CYP3A4ALDH1A1TDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109971151-B Bisphthalonitrile resin fiber reinforced material containing triaryl s-triazine structure and preparation method thereof 大连理工大学 2021-09-17 CN disclosed
CN-113147105-A Porous polyimide oil storage and retention structure and preparation method and application thereof 中国科学院兰州化学物理研究所 2021-07-23 CN disclosed