SCHEMBL28611577

SCHEMBL28611577

COc1ccc(C2(CBr)OC[C@@H](C)O2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
CHRNA1 P02708 1/20 0.39
CHRNG P07510 1/20 0.39
CHRNB1 P11230 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRND Q07001 1/20 0.39
HSD11B1 P28845 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
NPY1R P25929 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28605970 1.00 MAOB (0.41) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL11237185 0.86 MAOB (0.37) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL28614545 0.85 MAOB (0.42) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL28604796 0.83 CHRNA1 (0.37) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL28605862 0.83 GRIN1 (0.32)
SCHEMBL28608927 0.83 GRIN1 (0.32)
SCHEMBL28604802 0.83 CHRNA1 (0.37) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL11242518 0.83 CHRNA1 (0.37) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL28602336 0.82 SLC6A3 (0.36) MAOBMAOACHRNA1CHRNGCHRNB1
SCHEMBL28606554 0.82 SLC6A3 (0.36) MAOBMAOACHRNA1CHRNGCHRNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234066-A Propiconazole-like compound and preparation method and application thereof 浙江工业大学 2021-08-10 CN disclosed