SCHEMBL2861238

SCHEMBL2861238

COc1ccc(O)c(Oc2ccccc2)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 1/20 0.46
TTR P02766 5/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
CNR1 P21554 1/20 0.43
KMT2A Q03164 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
LTA4H P09960 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865457 0.83 KDM4E (0.51) KDM4EHSD17B10TTRMEN1LMNA
SCHEMBL9411633 0.80 HTT (0.50) KDM4EHSD17B10TTRMEN1KMT2A
SCHEMBL981350 0.80 KDM4E (0.49) KDM4EHSD17B10TTRMEN1LMNA
SCHEMBL29421917 0.79 MAOB (0.45) KDM4EHSD17B10LMNAMAPTCA1
SCHEMBL5141870 0.79 MAOB (0.45) KDM4EHSD17B10LMNAMAPTCA1
SCHEMBL8954581 0.79 CA1 (0.55) KDM4EHSD17B10TTRMEN1LMNA
SCHEMBL10931576 0.77 LTA4H (0.55) KDM4EHSD17B10TTRMEN1LMNA
SCHEMBL982234 0.76 TTR (0.50) KDM4EHSD17B10TTRMAPTKMT2A
SCHEMBL70459 0.75 ESR1 (0.49) KDM4EHSD17B10MEN1LMNAMAPT
SCHEMBL31203696 0.75 LMNA (0.42) KDM4EHSD17B10MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
CN-1757130-A Polymer electrolyte material, polymer electrolyte part, film electrode composite element and polymer electrolyte fuel cells TORAY INDUSTRIES (JP) 2006-04-05 CN disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed