Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.43 |
| ▸ | TUBB | P07437 | 8/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421917 | 1.00 | MAOB (0.45) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| SCHEMBL70459 | 0.86 | ESR1 (0.49) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| Hydrochloric Acid SCHEMBL11424028 | 0.84 | ESR1 (0.47) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| SCHEMBL68271 | 0.83 | TDP1 (0.44) | MAOBMAPTTP53CYP3A4CA1 | |
| SCHEMBL27423381 | 0.82 | MAPT (0.50) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| Hydrochloric Acid SCHEMBL28767777 | 0.82 | ESR1 (0.46) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| SCHEMBL1402414 | 0.81 | MAPT (0.48) | MAOBHIF1AEPAS1TUBB1TUBB4A | |
| SCHEMBL27944716 | 0.81 | PIM1 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9669244 | 0.80 | ALDH1A1 (0.47) | MAPTCA1CA2TSHRKDM4E | |
| SCHEMBL29793327 | 0.80 | ACHE (0.52) | MAPTCYP3A4CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299349-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | VESTLANDETS INNOVASJONSSELSKAP AS (NO) | 2024-09-12 | — | — | US | disclosed |
| EP-4021431-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | Vestlandets Innovasjonsselskap AS (NO) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021106947-A1 | NOVEL QUINONE DERIVATIVE AND ANTITRYPANOSOMAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | 国立大学法人群馬大学 | 2021-06-03 | — | — | WO | disclosed |
| WO-2021074614-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | VESTLANDETS INNOVASJONSSELSKAP AS (NO) | 2021-04-22 | — | — | WO | disclosed |
| US-8354454-B2 | Prodrugs of oxazolidinone CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20110218177-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME LLC | 2011-09-08 | — | — | US | disclosed |
| WO-2010039474-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-06 | — | — | US | disclosed |
| CN-1181075-C | Pyrimidine-4-keto compound, its preparation method and medicine composition containing them | ɪά��ʵ���� | 2004-12-22 | — | — | CN | disclosed |
| US-6809099-B2 | FOR THERAPY OF CANCER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-10-26 | — | — | US | disclosed |
| US-20040204419-A1 | Saframycins, analogues and uses thereof | MYERS ANDREW G (US) | 2004-10-14 | — | — | US | disclosed |
| US-6747032-B2 | DOUBLE ALPHA 2/5-HT 2C ANTAGONISTS USED TO TREAT DEPRESSION, IMPULSIVE BEHAVIOUR DISORDERS, ANXIETY, SCHIZOPHRENIA, PARKINSON'S DISEASE, COGNITIVE DISORDERS AND DISORDERS INVOLVING SEXUAL FUNCTION, SLEEP AND EATING | LES LABORATOIRES SERVIER (FR) | 2004-06-08 | — | — | US | disclosed |
| US-20030087916-A1 | Pyrimidin-4-one compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
| US-20030008873-A1 | Saframycins, analogues and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| CN-1381456-A | Pyrimidine-4-keto compound, its preparation method and medicine composition containing them | SIRVIR LAB (FR) | 2002-11-27 | — | — | CN | disclosed |
| EP-1256583-A1 | Pyrimidine-4-one derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-20020082424-A1 | Synthesis of CC-1065/duocarmycin analogs | THE SCRIPPS RESEARCH INSTITUTE | 2002-06-27 | — | — | US | disclosed |
| US-6310209-B1 | INTERMEDIATES INVOLVED IN THE 5-EXO-TRIG RADICAL CYCLIZATION OF AN ARYL HALIDE ONTO A TETHERED VINYL CHLORIDE FORMING THE DIHYDROINDOLE C-RING WITH CHLORINE INSTALLED AS A SUITABLE LEAVING GROUP FOR SUBSEQUENT CYCLOPROPANE SPIROCYCLIZATION. | THE SCRIPPS RESEARCH INSTITUTE | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204419-A1 | Saframycins, analogues and uses thereof | MYC, MAN1B1, MRPS18A | MAOB 1047/4885HIF1A 1157/4885EPAS1 4205/4885 |
| US-20110218177-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | CETP, SLCO2B1, OXA1L | MAOB 1069/4885HIF1A 568/4885EPAS1 1959/4885 |
| US-20020082424-A1 | Synthesis of CC-1065/duocarmycin analogs | CBR3, C2CD5, SIRT5 | MAOB 1934/4885HIF1A 3739/4885EPAS1 3297/4885 |
| US-20030008873-A1 | Saframycins, analogues and uses thereof | MYC, MAN1B1, MRPS18A | MAOB 1047/4885HIF1A 1157/4885EPAS1 4205/4885 |
| US-20070208086-A1 | UBIQUINONE ANALOGS AND METHODS OF USE | NDUFB7, NDUFB1, NDUFB3 | MAOB 364/4885HIF1A 2885/4885EPAS1 653/4885 |
| US-20030087916-A1 | Pyrimidin-4-one compounds | HTR2C, HTR1A, HTR4 | MAOB 206/4885HIF1A 535/4885EPAS1 1879/4885 |
| US-20240299349-A1 | TREATMENT OR PREVENTION OF LEUKAEMIA | BCL9, BCL9L, MCL1 | MAOB 2923/4885HIF1A 1886/4885EPAS1 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.