Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920692 | 0.82 | TSHR (0.36) | TSHRALDH1A1HPGDATMCES2 | |
| SCHEMBL28606229 | 0.80 | THRB (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL11696010 | 0.80 | ALDH1A1 (0.52) | TSHRALDH1A1HPGDTDP1ATM | |
| SCHEMBL1759582 | 0.76 | ALDH1A1 (0.52) | TSHRALDH1A1HPGDATMCES2 | |
| SCHEMBL17968134 | 0.76 | ALDH1A1 (0.36) | TSHRALDH1A1HPGDATMHCAR2 | |
| SCHEMBL19742957 | 0.76 | TSHR (0.41) | TSHRALDH1A1THRBHPGDPOLB | |
| SCHEMBL9402683 | 0.75 | TSHR (0.51) | TSHRALDH1A1THRBHPGDPOLB | |
| SCHEMBL11583525 | 0.74 | TSHR (0.84) | TSHRALDH1A1THRBHPGDPOLB | |
| SCHEMBL14893 | 0.74 | TSHR (0.84) | TSHRALDH1A1THRBHPGDPOLB | |
| SCHEMBL19066401 | 0.74 | TSHR (0.84) | TSHRALDH1A1THRBHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825776-A | Polymers having an upper critical solution temperature in aqueous solution | 波音公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113226379-A | Nanoparticle encapsulation targeting G protein-coupled receptors in endosomes | 武田药品工业株式会社 | 2021-08-06 | — | — | CN | disclosed |