Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682573 | 1.00 | AMPD2 (0.37) | AMPD2GAACYP2D6MEN1KMT2A | |
| SCHEMBL21682344 | 0.87 | L3MBTL1 (0.41) | GAAMEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL29422875 | 0.87 | L3MBTL1 (0.41) | GAAMEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL20397168 | 0.73 | GAA (0.46) | GAACYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL6324844 | 0.69 | GAA (0.51) | GAACYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL20399590 | 0.68 | DRD4 (0.44) | GAACYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL20399589 | 0.68 | DRD4 (0.44) | GAACYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL21819742 | 0.66 | RECQL (0.43) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL28623607 | 0.66 | RECQL (0.43) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL5029764 | 0.66 | AMPD2 (0.36) | AMPD2GAACYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272309-B | Tricyclic inhibitors of hepatitis b virus | 圣拉斐尔医院有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114555608-A | Oxamide substituted tricyclic inhibitors of hepatitis b virus | 分子遗传国家研究所(INGM) | 2022-05-27 | — | — | CN | disclosed |
| CN-113272309-A | Tricyclic inhibitors of hepatitis B virus | 圣拉斐尔医院有限公司 | 2021-08-17 | — | — | CN | disclosed |