Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612712 | 1.00 | GPR119 (0.40) | GPR119CHRM4SLC6A9DRD4HTR1A | |
| SCHEMBL24968239 | 0.85 | CHRM2 (0.43) | CHRM4SLC6A9 | |
| SCHEMBL24967976 | 0.84 | ACACB (0.38) | SLC6A9GRM1 | |
| SCHEMBL28627183 | 0.80 | CHRM4 (0.38) | GPR119CHRM4SLC6A9HTR1ADRD2 | |
| SCHEMBL28612099 | 0.73 | HTR1A (0.46) | HTR1ADRD2SIGMAR1KDM4ECYP1A2 | |
| SCHEMBL23744645 | 0.72 | MEN1 (0.43) | GRM1 | |
| SCHEMBL23727912 | 0.70 | CHRM4 (0.49) | CHRM4SLC6A9GRM1 | |
| SCHEMBL26087404 | 0.70 | CHRM4 (0.49) | CHRM4SLC6A9GRM1 | |
| SCHEMBL20158931 | 0.70 | GPR119 (0.61) | GPR119CHRM4SLC6A9GRM1 | |
| SCHEMBL23560705 | 0.70 | GPR119 (0.61) | GPR119CHRM4SLC6A9GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |