Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | AOC2 | O75106 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153055 | 0.84 | HPGD (0.49) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL2152568 | 0.81 | HPGD (0.58) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL27730852 | 0.80 | HPGD (0.61) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL5847146 | 0.79 | HPGD (0.64) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL29974170 | 0.79 | HPGD (0.59) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL860446 | 0.79 | HPGD (0.59) | HPGDTSHRNFKB1NFKB2RELA | |
| SCHEMBL5109501 | 0.79 | HPGD (0.64) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL1519327 | 0.79 | HPGD (0.64) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL2103264 | 0.78 | POLB (0.42) | HPGDTSHRCYP2D6OPRK1NFKB1 | |
| SCHEMBL15796618 | 0.78 | GLS (0.47) | CYP2D6OPRK1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660205-B | Heterocyclic compounds as LSD1 inhibitors | 因赛特公司 | 2021-08-27 | — | — | CN | claimed |
| CN-107660205-B | Heterocyclic compounds as LSD1 inhibitors | 因赛特公司 | 2021-08-27 | — | — | CN | disclosed |