Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | AOC2 | O75106 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974170 | 1.00 | HPGD (0.59) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL27730852 | 0.86 | HPGD (0.61) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL1519327 | 0.85 | HPGD (0.64) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL5109501 | 0.85 | HPGD (0.64) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL5847146 | 0.85 | HPGD (0.64) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL1757052 | 0.83 | HPGD (0.58) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL2176045 | 0.83 | HPGD (0.58) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL2152568 | 0.83 | HPGD (0.58) | HPGDTSHRAOC2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11343820 | 0.83 | HPGD (0.62) | HPGDTSHRAOC2MAOAMAOB | |
| SCHEMBL25999883 | 0.82 | AOC2 (0.61) | HPGDTSHRAOC2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624095-B | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-09-13 | — | — | CN | claimed |
| CN-115252621-B | Application of small molecular compound in preparation of medicine for treating osteoarthritis | 江苏省苏北人民医院 | 2023-06-30 | — | — | CN | claimed |
| CN-115252621-A | Application of small molecular compound in preparation of osteoarthritis treatment drug | 江苏省苏北人民医院 | 2022-11-01 | — | — | CN | claimed |
| EP-3728217-A1 | CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS | Ravenna Pharmaceuticals, Inc. (US) | 2020-10-28 | — | — | EP | claimed |
| US-20260115201-A1 | POTENTIAL THERAPEUTICS FOR FIBROSIS BY BLOCKING THE INCREASE OF A KEY ENZYME | TEXAS A & M UNIV SYS (US) | 2026-04-30 | — | — | US | disclosed |
| WO-2025106910-A1 | DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR | FLARE THERAPEUTICS INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-117624095-B | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-09-13 | — | — | CN | disclosed |
| CN-117624095-B | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-09-13 | — | — | CN | disclosed |
| CN-118533999-A | Analysis method for content uniformity of prucalopride succinate tablets | 江苏和汇医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2024121395-A1 | IAP INHIBITORS, METHODS OF MAKING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL SA (CH) | 2024-06-13 | — | — | WO | disclosed |
| CN-117624095-A | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-03-01 | — | — | CN | disclosed |
| CN-117624095-A | Synthesis method and application of novel chiral dihydrobenzofuran amide | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2024-03-01 | — | — | CN | disclosed |
| US-5122528-A | N-(1-azabicyclo(2.2.2)octyl) or N-((8-phenmethyl)-8-azabicyclo (3.2.1)octyl) benzofuryl, chromenyl or 1-benzoxepinyl carboxamides | ERBAMONT, INC. (US) | 1992-06-16 | — | — | US | disclosed |
| US-5114947-A | Benzofuran-7-carboxamides as anxiolytic agents | ERBAMONT INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0234872-B1 | CARBOXAMIDES USEFUL AS ANTIEMETIC OR ANTIPSYCHOTIC AGENTS | Erbamont Inc. (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0393838-A1 | Dopamine receptor ligands and imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0147044-B1 | BENZOFURANCARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | ADRIA LABORATORIES INC. (US) | 1990-04-25 | — | — | EP | disclosed |
| US-4888353-A | Carboxamides useful as antiemetic or antipsychotic agents | ERBAMONT, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0234872-A1 | Carboxamides useful as antiemetic or antipsychotic agents | Erbamont Inc. (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0147044-A2 | Benzofurancarboxamides, process for their preparation and pharmaceutical preparations containing them | ADRIA LABORATORIES INC. (US) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260115201-A1 | POTENTIAL THERAPEUTICS FOR FIBROSIS BY BLOCKING THE INCREASE OF A KEY ENZYME | DDX3X, DDX39B, DDX1 | HPGD 4065/4885TSHR 4469/4885AOC2 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.