SCHEMBL29974170

SCHEMBL29974170

NC(=O)C1Cc2ccccc2O1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
AOC2 O75106 5/20 0.55
MAOA P21397 5/20 0.55
MAOB P27338 5/20 0.55
DAO P14920 1/20 0.55
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860446 1.00 HPGD (0.59) HPGDTSHRAOC2MAOAMAOB
SCHEMBL27730852 0.86 HPGD (0.61) HPGDTSHRAOC2MAOAMAOB
SCHEMBL1519327 0.85 HPGD (0.64) HPGDTSHRAOC2MAOAMAOB
SCHEMBL5109501 0.85 HPGD (0.64) HPGDTSHRAOC2MAOAMAOB
SCHEMBL5847146 0.85 HPGD (0.64) HPGDTSHRAOC2MAOAMAOB
SCHEMBL1757052 0.83 HPGD (0.58) HPGDTSHRAOC2MAOAMAOB
SCHEMBL2176045 0.83 HPGD (0.58) HPGDTSHRAOC2MAOAMAOB
SCHEMBL2152568 0.83 HPGD (0.58) HPGDTSHRAOC2MAOAMAOB
Hydrochloric Acid SCHEMBL11343820 0.83 HPGD (0.62) HPGDTSHRAOC2MAOAMAOB
SCHEMBL25999883 0.82 AOC2 (0.61) HPGDTSHRAOC2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794896-A Protease inhibitors for the treatment of coronavirus infections 斯克里普斯研究学院 2024-03-29 CN claimed
WO-2025037323-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DRY EYE DISEASE AND ASSOCIATED DISORDERS KOTHAPUVARI PAVAN KUMAR (IN) 2025-02-20 WO disclosed
CN-118239937-A Compounds, compositions, and methods 戴纳立制药公司 2024-06-25 CN disclosed
CN-117794896-A Protease inhibitors for the treatment of coronavirus infections 斯克里普斯研究学院 2024-03-29 CN disclosed
CN-115252621-B Application of small molecular compound in preparation of medicine for treating osteoarthritis 江苏省苏北人民医院 2023-06-30 CN disclosed
EP-4081218-A1 ORALLY DISSOLVING FORMULATIONS OF PRUCALOPRIDE Shilpa Medicare Limited (IN) 2022-11-02 EP disclosed
CN-115252621-A Application of small molecular compound in preparation of osteoarthritis treatment drug 江苏省苏北人民医院 2022-11-01 CN disclosed
CN-115252621-A Application of small molecular compound in preparation of osteoarthritis treatment drug 江苏省苏北人民医院 2022-11-01 CN disclosed