Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14008630 | 1.00 | AAK1 (0.42) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL30912596 | 0.89 | ADORA1 (0.44) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL30912497 | 0.89 | ADORA1 (0.44) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL25173080 | 0.88 | PPARG (0.40) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL8766144 | 0.88 | CTSS (0.44) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL6661008 | 0.88 | CTSS (0.44) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL4778626 | 0.88 | CTSS (0.44) | AAK1ADORA1RENMMP13ITGB3 | |
| SCHEMBL2476924 | 0.87 | MMP13 (0.46) | RENMMP13ITGB3ITGA2BSLC7A5 | |
| SCHEMBL1401042 | 0.87 | MMP13 (0.46) | RENMMP13ITGB3ITGA2BSLC7A5 | |
| SCHEMBL65502 | 0.87 | MMP13 (0.46) | RENMMP13ITGB3ITGA2BSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053723-B | Sulfonamide derivatives and pharmaceutical use thereof | EA制药株式会社 | 2021-09-03 | — | — | CN | disclosed |