SCHEMBL1401042

SCHEMBL1401042

CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.46
REN P00797 1/20 0.46
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
ATM Q13315 1/20 0.44
ITGA4 P13612 1/20 0.43
ITGB7 P26010 1/20 0.43
ACE P12821 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
CTSS P25774 2/20 0.42
ADAMTS5 Q9UNA0 1/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
CTSK P43235 1/20 0.42
CYP1A2 P05177 1/20 0.42
SLC7A5 Q01650 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2476924 1.00 MMP13 (0.46) MMP13RENITGB3ITGA2BATM
SCHEMBL65502 1.00 MMP13 (0.46) MMP13RENITGB3ITGA2BATM
SCHEMBL30688558 0.95 ITGB3 (0.45) MMP13RENITGB3ITGA2BATM
SCHEMBL22457743 0.95 ITGB3 (0.45) MMP13RENITGB3ITGA2BATM
SCHEMBL30688551 0.95 ITGB3 (0.45) MMP13RENITGB3ITGA2BATM
SCHEMBL18248052 0.92 ALDH1A1 (0.48) MMP13RENITGB3ITGA2BACE
SCHEMBL1401223 0.92 ALDH1A1 (0.48) MMP13RENITGB3ITGA2BACE
SCHEMBL28518117 0.92 ALDH1A1 (0.48) MMP13RENITGB3ITGA2BACE
SCHEMBL29624556 0.92 ALDH1A1 (0.48) MMP13RENITGB3ITGA2BACE
SCHEMBL8911125 0.92 ALDH1A1 (0.48) MMP13RENITGB3ITGA2BACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118007135-A Corrosion inhibition method for inhibiting metal corrosion in sulfur-containing medium 福建理工大学 2024-05-10 CN claimed
CN-109320590-B Synthetic route to the antibiotic teixobactin and analogues thereof 清华大学 2021-03-02 CN claimed
CN-109320590-A The synthetic route of antibiotic teixobactin and the like 清华大学 2019-02-12 CN claimed
CN-103965299-B A kind of ring pentapeptide and synthetic method thereof and application 暨南大学 2016-07-13 CN claimed
CN-103965299-A Cyclic pentapeptide as well as synthetic method and application thereof UNIV JINAN 2014-08-06 CN claimed
CN-101274958-A Bioactive peptide, preparation thereof and application thereof OCEAN UNIV CHINA (CN) 2008-10-01 CN claimed
US-12435108-B2 Teixobactin analogue and use thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2025-10-07 US disclosed
WO-2024256834-A1 TEIXOBACTINS ANALOGUES AS ANTI-BIOFILM AGENTS UNIVERSITY OF LIVERPOOL (GB) 2024-12-19 WO disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-118007135-A Corrosion inhibition method for inhibiting metal corrosion in sulfur-containing medium 福建理工大学 2024-05-10 CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116981672-A Macrocyclic compounds as CFTR modulators 爱杜西亚药品有限公司 2023-10-31 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
WO-1998019699-A1 USE OF GROWTH HORMONE OR A GROWTH HORMONE SECRETAGOGUE FOR PROMOTING BONE FORMATION NOVO NORDISK A/S (DK) 1998-05-14 WO disclosed
CN-1176645-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1998-03-18 CN disclosed
WO-1997046252-A1 GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS NOVO NORDISK A/S (DK) 1997-12-11 WO disclosed
EP-0805816-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-11-12 EP disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed
EP-0728145-A1 ENDOTHELIN RECEPTOR ANTAGONISTS Ciba-Geigy Japan Limited (JP) 1996-08-28 EP disclosed
WO-1995012611-A1 ENDOTHELIN RECEPTOR ANTAGONISTS JAPAT LTD. (CH) 1995-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435108-B2 Teixobactin analogue and use thereof TALDO1, NAMPT, TES MMP13 828/4885REN 150/4885ITGB3 4122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.