Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624308 | 0.83 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL28624310 | 0.83 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL28613201 | 0.81 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL28613203 | 0.81 | EPHX2 (0.44) | EPHX2 | |
| SCHEMBL28615511 | 0.79 | TGM2 (0.54) | — | |
| SCHEMBL19708437 | 0.78 | EPHX1 (0.46) | ALDH1A1EPHX2MAPTGAAKMT2A | |
| SCHEMBL28581494 | 0.78 | EPHX1 (0.46) | ALDH1A1EPHX2MAPTGAAKMT2A | |
| SCHEMBL21009781 | 0.77 | EPHX1 (0.46) | ALDH1A1EPHX2MAPTGAAKMT2A | |
| SCHEMBL20873024 | 0.76 | DPP7 (0.41) | EPHX2 | |
| SCHEMBL28628330 | 0.76 | DPP7 (0.41) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |