⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722261 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL6770426 | 0.77 | CA2 (0.33) | — | |
| SCHEMBL8322528 | 0.74 | DPP4 (0.32) | — | |
| SCHEMBL1179454 | 0.74 | TP53 (0.33) | — | |
| Sulfuric Acid SCHEMBL28491424 | 0.74 | CA5A (0.33) | — | |
| SCHEMBL6776437 | 0.72 | — | — | |
| SCHEMBL983310 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL5072251 | 0.71 | — | — | |
| SCHEMBL17022951 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL576078 | 0.71 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113287600-B | Perfusion circuit and system for perfusion of isolated liver and system for preservation thereof | 特兰斯迈迪茨公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-113287600-A | Perfusion circuit and system for perfusion of isolated liver and system for preservation thereof | 特兰斯迈迪茨公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-106659151-B | Isolated organ care system | 特兰斯迈迪茨公司 | 2021-06-08 | — | — | CN | disclosed |