Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612356 | 0.79 | PTGS2 (0.49) | LMNASMN1; SMN2HTTMAPK1ALDH1A1 | |
| SCHEMBL28606507 | 0.79 | PTGS2 (0.49) | GSK3BGSK3AALDH1A1HPGD | |
| SCHEMBL1420343 | 0.69 | ACHE (0.43) | LMNASMN1; SMN2HTTGAAPOLB | |
| SCHEMBL22031215 | 0.68 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2HTTGAAPOLB | |
| SCHEMBL20577200 | 0.68 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2HTTGAAPOLB | |
| SCHEMBL16140281 | 0.68 | ALDH1A1 (0.65) | LMNASMN1; SMN2HTTPOLBMAPK1 | |
| SCHEMBL1419953 | 0.68 | HSD17B10 (0.41) | LMNAGAAARMAPK1ALDH1A1 | |
| SCHEMBL28198 | 0.66 | CA1 (0.67) | LMNAGAAPOLBMAPK1ALDH1A1 | |
| SCHEMBL6423919 | 0.66 | CA1 (0.67) | LMNAGAAPOLBMAPK1ALDH1A1 | |
| Methyl Alcohol SCHEMBL27456236 | 0.66 | HSD17B10 (0.70) | LMNAMAPK1ALDH1A1ACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586397-B | Method for preparing tetronic acid by cyclizing enolization of propargyl alcohol and carbon dioxide | 四川大学 | 2021-07-02 | — | — | CN | disclosed |