Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733710 | 0.87 | HSD11B1 (0.57) | HSD11B1HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL7278801 | 0.83 | HDAC1 (0.48) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 | |
| SCHEMBL9461582 | 0.83 | HDAC1 (0.45) | HSD11B1HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL837205 | 0.82 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 | |
| SCHEMBL8965454 | 0.82 | SLC6A2 (0.45) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL23364678 | 0.82 | ALDH1A1 (0.43) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 | |
| SCHEMBL21245020 | 0.81 | MEN1 (0.43) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 | |
| SCHEMBL17647438 | 0.81 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 | |
| SCHEMBL14177598 | 0.80 | HSD11B1 (0.53) | HSD11B1L3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL14618383 | 0.79 | HDAC1 (0.39) | HDAC1HDAC8HDAC6ALDH1A1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479967-A | Biliverdin compound and preparation method and application thereof | 百顺药业有限公司 | 2021-03-12 | — | — | CN | disclosed |