Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27380229 | 0.82 | KCNH2 (0.45) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL28613401 | 0.82 | HSD11B1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL23364678 | 0.81 | ALDH1A1 (0.43) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL6733710 | 0.79 | HSD11B1 (0.57) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL585895 | 0.79 | HDAC1 (0.41) | HDAC1HDAC8HDAC6 | |
| SCHEMBL27845695 | 0.79 | HDAC1 (0.41) | HDAC1HDAC8HDAC6 | |
| SCHEMBL9461582 | 0.78 | HDAC1 (0.45) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL7278801 | 0.78 | HDAC1 (0.48) | HDAC1HDAC8HDAC6ALDH1A1GAA | |
| SCHEMBL28088744 | 0.78 | HDAC1 (0.45) | HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL837205 | 0.78 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |