Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382216 | 0.98 | TDP1 (0.39) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL29930678 | 0.79 | TDP1 (0.37) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL101218 | 0.71 | DGAT1 (0.46) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL284141 | 0.71 | APLNR (0.55) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL1950611 | 0.71 | — | — | |
| SCHEMBL1522412 | 0.69 | DGAT1 (0.44) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL9409065 | 0.69 | — | — | |
| SCHEMBL6272856 | 0.69 | DGAT1 (0.44) | TDP1DGAT1CA1CA2CA7 | |
| SCHEMBL17960 | 0.69 | — | — | |
| SCHEMBL8428038 | 0.69 | DGAT1 (0.39) | TDP1DGAT1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292591-A | Synthesis method and application of 1, 3-bis (isocyanatoalkyl) -1,1,3, 3-tetramethyldisiloxane | 唐山三孚新材料有限公司 | 2021-08-24 | — | — | CN | disclosed |