Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613899 | 1.00 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28618546 | 0.89 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21670190 | 0.89 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21699995 | 0.89 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21670200 | 0.87 | — | — | |
| SCHEMBL21699976 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL29592764 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL21670196 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL21700019 | 0.86 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2KMT2ATP53 | |
| SCHEMBL21682570 | 0.84 | LMNA (0.40) | ALDH1A1LMNASMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272309-B | Tricyclic inhibitors of hepatitis b virus | 圣拉斐尔医院有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113272309-A | Tricyclic inhibitors of hepatitis B virus | 圣拉斐尔医院有限公司 | 2021-08-17 | — | — | CN | disclosed |