Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921103 | 0.87 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL6430240 | 0.87 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL11482408 | 0.84 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL5520683 | 0.83 | DRD2 (0.59) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL3729817 | 0.81 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL11170777 | 0.79 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL28017200 | 0.79 | MAPT (0.58) | ALDH1A1POLBMAPTLMNAHDAC3 | |
| SCHEMBL30051979 | 0.78 | MAPT (0.67) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL4333871 | 0.78 | POLB (0.60) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B | |
| SCHEMBL18415563 | 0.78 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1DRD2HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221612-A | Preparation method of l- [2- (2, 4-dimethylbenzenesulfide) -phenyl ] piperazine halogen acid salt | 浙江华海药业股份有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-116693419-A | Preparation method of heptafluoroisobutyronitrile | 浙江省化工研究院有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-115850233-A | Synthetic method of apalutamide | 南京方生和医药科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-118221612-A | Preparation method of l- [2- (2, 4-dimethylbenzenesulfide) -phenyl ] piperazine halogen acid salt | 浙江华海药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116693419-A | Preparation method of heptafluoroisobutyronitrile | 浙江省化工研究院有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-115850233-A | Synthetic method of apalutamide | 南京方生和医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113402466-B | Apaglucone intermediate and method for preparing apalone | 南京方生和医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113292535-B | Method for preparing apaluamide intermediate and apaluamide | 南京方生和医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114094032-B | Organic electroluminescent device and electronic apparatus | 北京莱特众成光电材料科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114094032-A | Organic electroluminescent device and electronic apparatus | 北京莱特众成光电材料科技有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-113402466-A | Apaglucone intermediate and method for preparing apalone | 南京方生和医药科技有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-113292535-A | Method for preparing apaluamide intermediate and apaluamide | 南京方生和医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |