SCHEMBL2861394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2865471	0.90	CYP3A4 (0.45)	SLC22A12CA1CA2ALDH1A1GAA
	SCHEMBL2861760	0.90	GAA (0.44)	HSP90AB1CA12CA9ALDH1A1GAA
	SCHEMBL2863503	0.89	L3MBTL1 (0.40)	HSP90AB1CA12CA9EGFRALDH1A1
	SCHEMBL2865023	0.86	AKR1C3 (0.44)	ALDH1A1MAPTHTT
	SCHEMBL2861252	0.86	SMN1; SMN2 (0.38)	HSP90AB1CA12CA1CA2CA7
	SCHEMBL2860161	0.85	CYP1A2 (0.50)	CA12CA1CA2CA7CA9
	SCHEMBL2856141	0.85	VNN1 (0.38)	ALDH1A1GAAGFER
	SCHEMBL2860145	0.85	TUBB4A (0.48)	SLC22A12ALDH1A1GAALMNAHTT
	SCHEMBL2867456	0.85	SLC22A12 (0.42)	SLC22A12EYA3CA2ESR1ESR2
	SCHEMBL2861691	0.84	SMN1; SMN2 (0.42)	HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.