Ornithine Aketoglutarate

Ornithine Aketoglutarate

SCHEMBL28614002

C1CCCCC1.NCCCC(N)C(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.75
ARG2 P78540 4/20 0.50
ARG1 P05089 3/20 0.50
NOS2 P35228 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
GLA P06280 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
APEX1 P27695 1/20 0.48
GRM8 O00222 1/20 0.48
GRM6 O15303 1/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GRIK1 P39086 1/20 0.48
GRM5 P41594 1/20 0.48
GRIA1 P42261 1/20 0.48
GRIA2 P42262 1/20 0.48
GRIA3 P42263 1/20 0.48
SLC1A3 P43003 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine Aketoglutarate SCHEMBL28343603 1.00 GSR (0.75) GSRARG2ARG1NOS2CYP1A2
Lysine SCHEMBL23728835 0.93 GSR (0.87) GSRARG2ARG1NOS2CYP1A2
Lysine SCHEMBL18986644 0.93 GSR (0.87) GSRARG2ARG1NOS2CYP1A2
D-Ornithine SCHEMBL43724 0.93
Ornithine Aketoglutarate SCHEMBL42530 0.93 GSR (0.86) GSRARG2ARG1NOS2CYP1A2
Ornithine SCHEMBL30695803 0.93
D-Ornithine SCHEMBL1537220 0.93 GSR (0.86) GSRARG2ARG1NOS2CYP1A2
Ornithine Aketoglutarate SCHEMBL8578 0.93
Ornithine SCHEMBL624782 0.93 GSR (0.86) GSRARG2ARG1NOS2CYP1A2
Ornithine Aketoglutarate SCHEMBL1326163 0.93 GSR (0.86) GSRARG2ARG1NOS2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452863-B Application of ornithine cyclohexane enzyme in improving yield of iturin A produced by bacillus amyloliquefaciens 湖北大学 2021-08-27 CN claimed
CN-110452863-B Application of ornithine cyclohexane enzyme in improving yield of iturin A produced by bacillus amyloliquefaciens 湖北大学 2021-08-27 CN disclosed
CN-110452863-B Application of ornithine cyclohexane enzyme in improving yield of iturin A produced by bacillus amyloliquefaciens 湖北大学 2021-08-27 CN disclosed
CN-110452863-B Application of ornithine cyclohexane enzyme in improving yield of iturin A produced by bacillus amyloliquefaciens 湖北大学 2021-08-27 CN disclosed