Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614142 | 0.91 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28605624 | 0.91 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28597276 | 0.91 | ACACB (0.51) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28601559 | 0.90 | ACACB (0.43) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28614290 | 0.85 | MEN1 (0.46) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28614292 | 0.85 | MEN1 (0.46) | MEN1KMT2APTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28593886 | 0.85 | ACACB (0.57) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28610083 | 0.83 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28614161 | 0.80 | ACACB (0.45) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL31124491 | 0.78 | SYK (0.55) | MEN1KMT2APTGS1PTGS2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |