Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.36 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614142 | 0.86 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28605624 | 0.86 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28603240 | 0.85 | KDM4E (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28603239 | 0.85 | KDM4E (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28614149 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28614161 | 0.83 | ACACB (0.45) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28597276 | 0.82 | ACACB (0.51) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28601559 | 0.82 | ACACB (0.43) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL31124490 | 0.80 | BTK (0.54) | MEN1KMT2AOPRK1 | |
| SCHEMBL28610085 | 0.80 | BTK (0.54) | MEN1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |