Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679621 | 0.95 | ACACB (0.46) | CYP11B2ACACBATMGPR119MAPT | |
| SCHEMBL12723192 | 0.94 | CYP3A4 (0.48) | CYP11B2ACACBATMGPR119MAPT | |
| SCHEMBL12480371 | 0.86 | GPR119 (0.56) | ATMGPR119MAPTOGA | |
| SCHEMBL23742297 | 0.82 | CYP11B2 (0.56) | CYP11B2ACACBGPR119MAPTCYP3A4 | |
| SCHEMBL28597527 | 0.82 | ACACB (0.54) | ACACBNPSR1CYP3A4OGA | |
| SCHEMBL24992878 | 0.81 | ATM (0.46) | CYP11B2ACACBATMGPR119MAPT | |
| SCHEMBL485352 | 0.81 | CYP3A4 (0.62) | CYP11B2GPR119MAPTCYP3A4SCD5 | |
| SCHEMBL484867 | 0.81 | CYP11B2 (0.54) | CYP11B2ACACBGPR119MAPTCYP3A4 | |
| SCHEMBL25035458 | 0.80 | GPR119 (0.45) | CYP11B2ACACBGPR119MAPT | |
| SCHEMBL17830844 | 0.78 | ATM (0.42) | ATMGPR119MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810108-B | 2, 8-diaza-spiro- [4,5] -decane pyrimidine-hydroxamic acid compound and application thereof | 华东理工大学 | 2021-08-06 | — | — | CN | disclosed |