Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464861 | 0.86 | ALDH1A1 (0.44) | NPC1RAB9AKMT2AGAALMNA | |
| SCHEMBL6630978 | 0.84 | SMN1; SMN2 (0.50) | HTTNPC1RAB9AKMT2AHPGD | |
| SCHEMBL29144839 | 0.79 | SIGMAR1 (0.44) | KMT2ATSHRSIGMAR1POLBALDH1A1 | |
| SCHEMBL7233912 | 0.76 | ALDH1A1 (0.43) | HTTLMNATSHRKDM4EALDH1A1 | |
| SCHEMBL9690903 | 0.71 | CHRM2 (0.51) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL6574227 | 0.70 | SLC18A3 (0.45) | HTTRAB9ALMNASIGMAR1OPRM1 | |
| SCHEMBL18429032 | 0.70 | CHRM2 (0.50) | ACHENPC1RAB9ALMNAKDM4E | |
| SCHEMBL31218745 | 0.69 | JAK2 (0.45) | KMT2A | |
| SCHEMBL6169050 | 0.69 | ALDH1A1 (0.52) | RAB9AKMT2ALMNATSHRSIGMAR1 | |
| SCHEMBL6164244 | 0.69 | ALDH1A1 (0.41) | HTTNPC1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292484-B | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2022-11-15 | — | — | CN | claimed |
| CN-113292484-A | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113292484-B | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113292484-B | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113292484-B | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113292484-A | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-113292484-A | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-113292484-A | 3- (4-methylpiperidine-1-yl) -3-benzylurea compound and analogue, preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |