Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169050 | 0.82 | ALDH1A1 (0.52) | SLC18A3ALDH1A1POLBLMNARAB9A | |
| SCHEMBL31218745 | 0.73 | JAK2 (0.45) | HSD11B1L3MBTL1 | |
| SCHEMBL28614652 | 0.70 | ACHE (0.46) | ALDH1A1POLBLMNARAB9ASIGMAR1 | |
| SCHEMBL6574027 | 0.70 | DRD2 (0.48) | SLC18A3ALDH1A1POLBRAB9ASIGMAR1 | |
| SCHEMBL31073550 | 0.70 | KCNH2 (0.56) | SLC18A3ALDH1A1KCNH2HRH3LMNA | |
| SCHEMBL6482121 | 0.70 | CCR5 (0.43) | OPRM1 | |
| SCHEMBL6482118 | 0.70 | CCR5 (0.43) | OPRM1 | |
| SCHEMBL26986820 | 0.70 | SLC18A3 (0.58) | SLC18A3SIGMAR1OGAHTTSMN1; SMN2 | |
| SCHEMBL7712884 | 0.69 | AKT1 (0.44) | HSD11B1L3MBTL1CHRM4 | |
| SCHEMBL6574730 | 0.69 | SLC18A3 (0.50) | SLC18A3ALDH1A1KCNH2HRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |