Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR1E | P28566 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | ITGAL | P20701 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24106817 | 1.00 | ALOX5 (0.48) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL21048720 | 0.87 | ITGB2 (0.59) | ALOX5ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL5808674 | 0.87 | HTR1D (0.51) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL7598348 | 0.84 | ITGB2 (0.55) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL4535076 | 0.82 | HTR1D (0.48) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL13912236 | 0.82 | HTR1D (0.49) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL10664287 | 0.81 | CYP3A4 (0.49) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL13897023 | 0.81 | CYP3A4 (0.49) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL29002721 | 0.81 | HTR1D (0.48) | ALOX5HTR1DHTR2CHTR1EHTR2B | |
| SCHEMBL23901492 | 0.80 | CYP3A4 (0.48) | ALOX5HTR1DHTR2CHTR1EHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114096514-A | Amino acid based polymerizable compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2022-02-25 | — | — | CN | claimed |
| CN-114096514-A | Amino acid based polymerizable compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-113038959-A | Composition for treating oxidative stress-related skin diseases and skin aging and diagnosis of oxidative stress-related skin diseases | S-生物医药有限公司 | 2021-06-25 | — | — | CN | disclosed |