SCHEMBL28615365

SCHEMBL28615365

FC(F)(F)COc1ccc(C(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.49
CYP17A1 P05093 2/20 0.49
CYP2C19 P33261 2/20 0.49
GPR3 P46089 1/20 0.42
MAPT P10636 4/20 0.42
ALDH1A1 P00352 3/20 0.42
SCN5A Q14524 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
LMNA P02545 3/20 0.37
PAX8 Q06710 2/20 0.37
CACNA1G O43497 1/20 0.36
CACNA1H O95180 1/20 0.36
CNR2 P34972 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1I Q9P0X4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498377 0.82 ALDH1A1 (0.56) CYP2C9CYP17A1CYP2C19GPR3MAPT
SCHEMBL9742245 0.81 CYP2C9 (0.54) CYP2C9CYP17A1CYP2C19GPR3MAPT
SCHEMBL5018838 0.80 CYP17A1 (0.57) CYP2C9CYP17A1CYP2C19MAPTALDH1A1
SCHEMBL21467379 0.78 CYP2C9 (0.55) CYP2C9CYP17A1CYP2C19GPR3MAPT
SCHEMBL14416502 0.77 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2L3MBTL1GAA
SCHEMBL2691207 0.77 CYP2C9 (0.54) CYP2C9CYP17A1CYP2C19GPR3MAPT
SCHEMBL7930470 0.77 CYP2C9 (0.47) CYP2C9CYP17A1CYP2C19GPR3MAPT
SCHEMBL18380932 0.76 SCN5A (0.56) CYP2C9CYP17A1CYP2C19GPR3MAPT
Hydrochloric Acid SCHEMBL28675346 0.76 CYP2C9 (0.53) CYP2C9CYP17A1CYP2C19GPR3MAPT
Hydrochloric Acid SCHEMBL2716164 0.76 CYP2C9 (0.53) CYP2C9CYP17A1CYP2C19GPR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214425-A Modified polytetrafluoroethylene and preparation method and application thereof 深圳市圣一科技有限公司 2021-08-06 CN disclosed